منابع مشابه
Inheritance of DNA Methylation in Plant Genome
Genomic DNA contains not only information of DNA sequence, but also epigenetic information that is the direct DNA modification by methylation (the addition of methyl group to the 5th carbon of pyrimidine ring of cytosine) and histone modifications (acetylation, methylation, etc). Epigenetic information is closely related to regulation of gene expression. If a methyl group is dislocated to posit...
متن کاملMitochondrial DNA Mutations, Pathogenicity and Inheritance
Mitochondria contain their own DNA (mtDNA), which codes for 13 proteins (all subunits of the respiratory chain complexes), 22 tRNAs and 2 rRNAs. Several mtDNA point mutations as well as deletions have been shown to be causative in well-defined mitochondrial disorders. A mixture of mutated and wild type mtDNA (heteroplasmy) is found in most of these disorders. Inheritance of mtDNA is maternal, a...
متن کاملDNA methylation and epigenetic inheritance in plants and filamentous fungi.
Plants and filamentous fungi share with mammals enzymes responsible for DNA methylation. In these organisms, DNA methylation is associated with gene silencing and transposon control. However, plants and fungi differ from mammals in the genomic distribution, sequence specificity, and heritability of methylation. We consider the role that transposons play in establishing methylation patterns and ...
متن کاملEpimutations, Inheritance and Causes of Aberrant DNA Methylation in Cancer
Epigenetic aberrations such as global hypomethylation and gene-specific hypermethylation are key events that underlie tumour development. Such scenarios are brought about by the loss of control of methylation patterns which typically are reversed in neoplasia in comparison to normal states. Despite the methylation process being termed epigenetic, suggesting that it is not a heritable condition,...
متن کاملEvolutionary Optimization for Problem Classes with Lamarckian Inheritance
The combination of evolution and learning as two natural principles of optimization, which work on different time scales, has been shown to be very efficient for optimization tasks. We investigate how this combination should be organized to achieve networks that can fast and reliably switch between related problems from one and the same class of problems during operation time. We analyze differ...
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ژورنال
عنوان ژورنال: Proceedings of the Japan Academy, Series B
سال: 2002
ISSN: 0386-2208,1349-2896
DOI: 10.2183/pjab.78.293